A client on prolonged cortisone therapy for adrenal insufficiency may experience which of the following side effects? Select all that apply.

Cortisone, a type of corticosteroid, is often prescribed for adrenal insufficiency, and prolonged use can lead to several notable side effects due to its effects on metabolism and fluid balance in the body.

Weight gain is a common side effect associated with prolonged cortisone therapy. Corticosteroids can cause increased appetite, leading to higher caloric intake. They also promote the accumulation of fat, particularly in the abdominal area, resulting in pronounced weight changes.

Moon face is another characteristic side effect of long-term corticosteroid therapy. This symptom is due to redistribution of fat and fluid retention, causing a rounded appearance in the face. It reflects the typical changes in body fat distribution associated with prolonged steroid use.

Weakness can occur due to muscle wasting. Long-term corticosteroid therapy can inhibit the synthesis of proteins, leading to muscle atrophy and weakness. This can significantly affect a person’s strength and mobility.

Elevated blood pressure is another potential complication of prolonged cortisone therapy. Corticosteroids can lead to sodium retention, increased blood volume, and ultimately higher blood pressure. This side effect is particularly important for monitoring in patients receiving long-term steroid therapy.

Recognizing these side effects is crucial for clinicians and patients receiving corticosteroid treatment, as they