When monitoring a client on cyclosporine after an organ transplant, which serious adverse effect should the nurse watch for?

The correct response is focused on the importance of monitoring kidney function, particularly through creatinine levels, in patients receiving cyclosporine after an organ transplant. Cyclosporine is an immunosuppressive medication commonly used to prevent organ rejection, but it is also known for its potential nephrotoxicity. This means that while cyclosporine protects the transplanted organ from being rejected by the immune system, it can adversely affect the kidneys, leading to elevated creatinine levels, which indicate impaired kidney function.

Monitoring creatinine is crucial because it provides key information regarding renal health, and an increase can suggest that the drug is causing damage to the kidneys or that the patient may have an additional underlying renal issue. In the context of organ transplantation, maintaining stable kidney function is vital since many transplant medications and the transplant itself can strain renal resources.

While the other choices refer to various bodily responses that may occur due to different conditions or medications, they do not specifically address the direct nephrotoxic effects of cyclosporine. Therefore, understanding and monitoring creatinine levels allows the healthcare provider to catch potential renal impairment early and adjust the treatment plan accordingly before significant complications arise.