Which symptom indicates possible ototoxicity during aminoglycoside treatment?

C. Tinnitus is a key symptom of possible ototoxicity during aminoglycoside treatment. Aminoglycosides, a class of antibiotics used to treat serious infections, have a known side effect profile that includes the potential for damage to the inner ear structures, leading to hearing-related issues. Tinnitus, characterized by a ringing or buzzing sound in the ears, often serves as an early indicator of ototoxicity. Recognizing this symptom is crucial for monitoring patients on aminoglycosides, as it may warrant further evaluation or adjustment of therapy to prevent permanent hearing loss.

In contrast, increased blood pressure, dry skin, and nausea are not directly associated with ototoxicity in the context of aminoglycoside use. Increased blood pressure can result from various factors, including medication side effects unrelated to ototoxicity, while dry skin and nausea might be side effects of different medications or physiological responses, but they do not indicate potential hearing impairment. Thus, the presence of tinnitus stands out as a hallmark symptom of ototoxicity associated with aminoglycoside treatment.